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Welcome to the Longevity Knowledge Center — your trusted source for clear, science-based insights into the biology of aging and the strategies to overcome it.

This is not hype. This is your roadmap to surviving—and thriving—into the era of radical life extension.

Whether you’re longevity-curious, health-optimized, or building your own protocol, this section will help you go from overwhelmed… to enlightened.

Living Long Enough To Live Forever

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David A. Sinclair

Immortality is Here / David A. Sinclair
Listing Category
Short Description
Harvard geneticist and NAD+ pioneer reshaping epigenetic-reprogramming research.
Description

David A. Sinclair is a tenured Professor of Genetics at Harvard Medical School and co‑director of the Paul F. Glenn Center for Biology of Aging Research. For more than two decades, his lab has investigated epigenetic drift, sirtuins, and NAD+ metabolism. His 'Information Theory of Aging' argues that age‑related decline stems from epigenetic information loss. Sinclair’s work with NAD+ precursors (NMN/NR) and partial reprogramming offers plausible routes to reset cellular age. Beyond academia he co‑founded Sirtris, MetroBiotech, and Tally Health, and hosts the 'Lifespan' podcast. He has ~100 k citations and 490 k X followers.

Website
https://www.linkedin.com/in/davidsinclairphd
Role Type
Scientist / Researcher / Entrepreneur
Focus Area
Epigenetic Reprogramming, NAD+, Sirtuins
Platform Reach
X (Twitter), Podcast, LinkedIn, Google Scholar
Affiliation
Harvard Medical School; Life Biosciences; Tally Health
Impact Level
≈100 k citations; 490 k X followers