Short Description Newcastle professor decoding autophagy and nutrient sensing.
Description Prof. Viktor Korolchuk leads the Cellular Gerontology group at Newcastle University’s world‑renowned Institute for Aging. His lab discovered how TFEB and mTORC1 coordinate lysosomal biogenesis and autophagic flux in response to amino‑acid availability. Korolchuk demonstrated that boosting autophagy via small‑molecule activators restores proteostasis and extends lifespan in model organisms, positioning lysosome–mTOR signaling as a prime drug target. He co‑founded Autolytix Therapeutics and advises the UK All‑Party Parliamentary Group for Longevity on nutrient‑sensing interventions.