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Welcome to the Longevity Knowledge Center — your trusted source for clear, science-based insights into the biology of aging and the strategies to overcome it.

This is not hype. This is your roadmap to surviving—and thriving—into the era of radical life extension.

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João F. Passos

Immortality is Here / João F. Passos
Listing Category
Short Description
Mayo Clinic scientist linking mitochondrial fission to senescence.
Description

Portuguese biologist João Passos discovered that dysfunctional mitochondria trigger the senescence‑associated secretory phenotype (SASP) via cytosolic mtDNA. He revealed that targeting Drp1‑mediated fission alleviates SASP in aged stem cells, suggesting novel senostatic strategies. Passos collaborates with Unity Biotechnology and lectures at Cold Spring Harbor courses on cellular aging.

Role Type
Scientist / Researcher
Focus Area
Mitochondrial Dynamics, Senescence, SASP
Platform Reach
PubMed, LinkedIn, Conferences
Affiliation
Mayo Clinic
Impact Level
30 k citations