Short Description Northwestern biochemist redefining mitochondria as signaling organelles.
Description Prof. Navdeep Chandel demonstrated that mitochondrial ROS are not merely by‑products but essential signaling molecules regulating HIF, AMPK, and histone demethylases—pathways intimately tied to aging. His book ‘Navigating Metabolism’ reframed the field, showing how metabolic substrates instruct cell fate and longevity through epigenetic enzymes. Chandel’s lab now screens mitohormetic compounds that mimic exercise‑induced ROS bursts to promote healthspan.
Platform Reach PubMed, Books, LinkedIn, Conferences